The U.S. Supreme Court is set to begin hearing oral arguments Monday in a Republican-led challenge to the national health care law that has convulsed the country and its political class for more than two years — and may well define President Obama's tenure in the White House.

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LAURA SULLIVAN, HOST:

It's WEEKENDS on ALL THINGS CONSIDERED from NPR News. I'm Laura Sullivan, in for Guy Raz.

The Republican nominating contest is back in the South today as primary voters cast their ballots in Louisiana. A little earlier, we caught up with NPR's national political correspondent Don Gonyea who's on the road in Louisiana. Don, where are you now?

Saturday should be another good day for Rick Santorum, as his strength has been in Southern states. Polls in Louisiana, which is holding its primary, also gave him a double-digit lead over Mitt Romney coming into the weekend.

The Sportsman's Paradise has 46 Republican delegates to send to the party's presidential-nominating convention. But the very helpful Frontloading HQ blog informs us that only 20 of 25 at-large delegates will be doled out based on Saturday's results.

A rally organizers have billed as the "largest secular event in world history" will be held on the National Mall today.

The Reason Rally will bring atheists and nonbelievers together in a hallowed American place.

But Paul Fidalgo of the Center for Inquiry, one of the organizations involved, says, "It's not a march on Washington where we're picketing anything. It's a celebration of the fact that the secular movement is really starting to come into its own."

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SCOTT SIMON, HOST:

This is WEEKEND EDITION from NPR News. I'm Scott Simon. Time for sports.

(SOUNDBITE OF MUSIC)

SIMON: And coming up, we'll talk about the scandal rocking the NFL. But first, in the NCAA last night: North Carolina needed overtime to put away Ohio. Kansas defeated NC State. Baylor beat Xavier. And Kentucky toppled Indiana 102 to 90. And with that win, the powerhouse Wildcats moved into the elite 8 of the tournament. NPR's Mike Pesca reports.

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SCOTT SIMON, HOST:

This week, Mitt Romney and Rick Santorum got their secret service code names. Mr. Romney is Javelin. Mr. Santorum is Petrus. We asked Ian Chillag and Mike Danforth from the NPR podcast How to Do Everything to look into how secret service code names are assigned.

IAN CHILLAG, BYLINE: Presidents have been getting codenames all the way back to Harry Truman. The secret service called him General.

MIKE DANFORTH, BYLINE: Here's historian Michael Beschloss.

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SCOTT SIMON, HOST:

This is WEEKEND EDITION from NPR News. I'm Scott Simon.

Be careful what you wish for. After John McCain so quickly clinched the Republican presidential nomination the last time around, the party changed its rules with an eye to extending their primary season, reaping public interest for months like the long Democratic primary season of 2008. You might wonder how they feel about that now. John McCain himself has dubbed this campaign the nastiest he's ever seen - akin to watching a Greek tragedy.